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Structural basis by which alternative splicing confers specificity in fibroblast growth factor receptors

Binding specificity between fibroblast growth factors (FGFs) and their receptors (FGFRs) is essential for mammalian development and is regulated primarily by two alternatively spliced exons, IIIb (“b”) and IIIc (“c”), that encode the second half of Ig-like domain 3 (D3) of FGFRs. FGF7 and FGF10 acti...

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I publikationen:Proc Natl Acad Sci U S A
Huvudupphov: Yeh, Brian K., Igarashi, Makoto, Eliseenkova, Anna V., Plotnikov, Alexander N., Sher, Ifat, Ron, Dina, Aaronson, Stuart A., Mohammadi, Moosa
Materialtyp: Artigo
Språk:Inglês
Utgiven: National Academy of Sciences 2003
Ämnen:
Biological Sciences
Länkar:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC151329/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12591959/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0436500100
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