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Structural basis by which alternative splicing confers specificity in fibroblast growth factor receptors

Binding specificity between fibroblast growth factors (FGFs) and their receptors (FGFRs) is essential for mammalian development and is regulated primarily by two alternatively spliced exons, IIIb (“b”) and IIIc (“c”), that encode the second half of Ig-like domain 3 (D3) of FGFRs. FGF7 and FGF10 acti...

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Detalhes bibliográficos
Main Authors: Yeh, Brian K., Igarashi, Makoto, Eliseenkova, Anna V., Plotnikov, Alexander N., Sher, Ifat, Ron, Dina, Aaronson, Stuart A., Mohammadi, Moosa
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC151329/
https://ncbi.nlm.nih.gov/pubmed/12591959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0436500100
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