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Structural basis by which alternative splicing confers specificity in fibroblast growth factor receptors

Binding specificity between fibroblast growth factors (FGFs) and their receptors (FGFRs) is essential for mammalian development and is regulated primarily by two alternatively spliced exons, IIIb (“b”) and IIIc (“c”), that encode the second half of Ig-like domain 3 (D3) of FGFRs. FGF7 and FGF10 acti...

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書誌詳細
出版年:Proc Natl Acad Sci U S A
主要な著者: Yeh, Brian K., Igarashi, Makoto, Eliseenkova, Anna V., Plotnikov, Alexander N., Sher, Ifat, Ron, Dina, Aaronson, Stuart A., Mohammadi, Moosa
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 2003
主題:
オンライン・アクセス:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC151329/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12591959/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0436500100
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