Pathological and physiological functions of presenilins

Mutations in PSEN1 and PSEN2 genes account for the majority of cases of early-onset familial Alzheimer disease. Since the first prediction of a genetic link between PSEN1 and PSEN2 with Alzheimer's disease, many research groups from both academia and pharmaceutical industry have sought to unrav...

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Detalhes bibliográficos
Main Authors: Vetrivel, Kulandaivelu S, Zhang, Yun-wu, Xu, Huaxi, Thinakaran, Gopal
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1513131/
https://ncbi.nlm.nih.gov/pubmed/16930451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1750-1326-1-4
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https://ncbi.nlm.nih.gov/pmc/articles/PMC1513131/
https://ncbi.nlm.nih.gov/pubmed/16930451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1750-1326-1-4