Structural requirements of ligands for the oxysterol liver X receptors LXRα and LXRβ

LXRα and -β are nuclear receptors that regulate the metabolism of several important lipids, including cholesterol and bile acids. Previously, we have proposed that LXRs regulate these pathways through their interaction with specific, naturally occurring oxysterols, including 22(R)-hydroxycholesterol...

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Dades bibliogràfiques

Publicat a:	Proc Natl Acad Sci U S A
Autors principals:	Janowski, Bethany A., Grogan, Michael J., Jones, Stacey A., Wisely, G. Bruce, Kliewer, Steven A., Corey, Elias J., Mangelsdorf, David J.
Format:	Artigo
Idioma:	Inglês
Publicat:	National Academy of Sciences 1999
Matèries:	Biological Sciences
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC15128/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9874807/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.1.266
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