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Neuroprotection with noninvasive neurotrophin delivery to the brain

Brain-derived neurotrophic factor (BDNF) is neuroprotective in the ischemic hippocampus if the neurotrophin is injected directly into the brain. However, the efficacy of BDNF via peripheral (i.v.) administration is limited by the lack of transport of the neurotrophin through the brain capillary wall...

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Detalhes bibliográficos
Main Authors: Wu, Dafang, Pardridge, William M.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC15126/
https://ncbi.nlm.nih.gov/pubmed/9874805
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