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The role of bile salt export pump mutations in progressive familial intrahepatic cholestasis type II
PFIC II is a subtype of progressive familial intrahepatic cholestasis (PFIC) that is associated with mutations in the ABCB11 gene encoding the bile salt export pump (BSEP). However it is not known how these mutations cause this disease. To evaluate these mechanisms, we introduced seven PFIC II–assoc...
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| Main Authors: | , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
American Society for Clinical Investigation
2002
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC151156/ https://ncbi.nlm.nih.gov/pubmed/12370274 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI15968 |
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