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Emergence of a dual-catalytic RNA with metal-specific cleavage and ligase activities: The spandrels of RNA evolution

In vitro selection, or directed molecular evolution, allows the isolation and amplification of rare sequences that satisfy a functional-selection criterion. This technique can be used to isolate novel ribozymes (RNA enzymes) from large pools of random sequences. We used in vitro evolution to select...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Landweber, Laura F., Pokrovskaya, Irina D.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: The National Academy of Sciences 1999
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC15112/
https://ncbi.nlm.nih.gov/pubmed/9874791
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