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Site-specific cleavage by metal ion cofactors and inhibitors of M1 RNA, the catalytic subunit of RNase P from Escherichia coli.
The location of phosphate residues involved in specific centers for binding of metal ions in M1 RNA, the catalytic RNA subunit of RNase P from Escherichia coli, was determined by analysis of induction of cleavage of RNA by metal ions. At pH 9.5, Mg2+ catalyzes cleavage of M1 RNA at five principal si...
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| Hauptverfasser: | , |
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| Format: | Artigo |
| Sprache: | Inglês |
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1991
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| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC52679/ https://ncbi.nlm.nih.gov/pubmed/1718000 |
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