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Site-specific cleavage by metal ion cofactors and inhibitors of M1 RNA, the catalytic subunit of RNase P from Escherichia coli.

The location of phosphate residues involved in specific centers for binding of metal ions in M1 RNA, the catalytic RNA subunit of RNase P from Escherichia coli, was determined by analysis of induction of cleavage of RNA by metal ions. At pH 9.5, Mg2+ catalyzes cleavage of M1 RNA at five principal si...

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Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Kazakov, S, Altman, S
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 1991
Témata:
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC52679/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1718000/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.20.9193
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