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Tr1 cell–dependent active tolerance blunts the pathogenic effects of determinant spreading
Experimental autoimmune encephalomyelitis (EAE) is a T cell–mediated autoimmune disease of the CNS. The current study shows that even in an acute episode of disease the autoimmune response spreads from one determinant on myelin basic protein (MBP) to the other linked determinant and that this spread...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Clinical Investigation
2002
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC151104/ https://ncbi.nlm.nih.gov/pubmed/12208871 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI15176 |
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