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Transcriptional control of viral gene therapy by cisplatin

Ionizing radiation (IR) and radical oxygen intermediates (ROIs) activate the early growth response-1 (Egr1) promoter through specific cis-acting sequences termed CArG elements. Ad.Egr.TNF.11D, a replication-deficient adenoviral vector containing CArG elements cloned upstream of the cDNA for human re...

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Detalhes bibliográficos
Main Authors: Park, James O., Lopez, Carlos A., Gupta, Vinay K., Brown, Charles K., Mauceri, Helena J., Darga, Thomas E., Manan, Abdullah, Hellman, Samuel, Posner, Mitchell C., Kufe, Donald W., Weichselbaum, Ralph R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2002
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC151093/
https://ncbi.nlm.nih.gov/pubmed/12163460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI15548
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