Thyroid-stimulating autoantibodies in Graves disease preferentially recognize the free A subunit, not the thyrotropin holoreceptor

Eitemau Tebyg

• Evidence that Shed Thyrotropin Receptor A Subunits Drive Affinity Maturation of Autoantibodies Causing Graves’ Disease
  gan: Mizutori, Yumiko, et al.
  Cyhoeddwyd: (2009)
• The thyrotropin receptor autoantigen in Graves disease is the culprit as well as the victim
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  Cyhoeddwyd: (2003)
• Thyrotropin-Blocking Autoantibodies and Thyroid-Stimulating Autoantibodies: Potential Mechanisms Involved in the Pendulum Swinging from Hypothyroidism to Hyperthyroidism or Vice Versa
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  Cyhoeddwyd: (2013)
• A Mouse Thyrotropin Receptor A-Subunit Transgene Expressed in Thyroiditis-Prone Mice May Provide Insight into Why Graves' Disease Only Occurs in Humans
  gan: McLachlan, Sandra M., et al.
  Cyhoeddwyd: (2019)
• Insight into Thyroid-Stimulating Autoantibody Interaction with the Thyrotropin Receptor N-Terminus Based on Mutagenesis and Re-Evaluation of Ambiguity in This Region of the Receptor Crystal Structure
  gan: Hamidi, Sepehr, et al.
  Cyhoeddwyd: (2011)