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Exceptional hyperthyroidism and a role for both major histocompatibility class I and class II genes in a murine model of Graves' disease.

Autoimmune hyperthyroidism, Graves' disease, can be induced by immunizing susceptible strains of mice with adenovirus encoding the human thyrotropin receptor (TSHR) or its A-subunit. Studies in two small families of recombinant inbred strains showed that susceptibility to developing TSHR antibodies...

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Váldodahkkit: Sandra M McLachlan, Holly A Aliesky, Chun-Rong Chen, Robert W Williams, Basil Rapoport
Materiálatiipa: Artigo
Giella:Inglês
Almmustuhtton: Public Library of Science (PLoS) 2011-01-01
Ráidu:PLoS ONE
Liŋkkat:http://europepmc.org/articles/PMC3124500?pdf=render
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