Opposite effects of cyclooxygenase-1 and -2 activity on the pressor response to angiotensin II

Therapeutic use of cyclooxygenase-inhibiting (COX-inhibiting) nonsteroidal antiinflammatory drugs (NSAIDs) is often complicated by renal side effects including hypertension and edema. The present studies were undertaken to elucidate the roles of COX1 and COX2 in regulating blood pressure and renal f...

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izdano v:	J Clin Invest
Principais autores:	Qi, Zhonghua, Hao, Chuan-Ming, Langenbach, Robert I., Breyer, Richard M., Redha, Reyadh, Morrow, Jason D., Breyer, Matthew D.
Format:	Artigo
Jezik:	Inglês
Izdano:	American Society for Clinical Investigation 2002
Teme:	Article
Online dostop:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC151026/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12093889/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI14752
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