Opposite effects of cyclooxygenase-1 and -2 activity on the pressor response to angiotensin II

Therapeutic use of cyclooxygenase-inhibiting (COX-inhibiting) nonsteroidal antiinflammatory drugs (NSAIDs) is often complicated by renal side effects including hypertension and edema. The present studies were undertaken to elucidate the roles of COX1 and COX2 in regulating blood pressure and renal f...

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Publicado en:	J Clin Invest
Autores principales:	Qi, Zhonghua, Hao, Chuan-Ming, Langenbach, Robert I., Breyer, Richard M., Redha, Reyadh, Morrow, Jason D., Breyer, Matthew D.
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	American Society for Clinical Investigation 2002
Materias:	Article
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC151026/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12093889/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI14752
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