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Opposite effects of cyclooxygenase-1 and -2 activity on the pressor response to angiotensin II

Therapeutic use of cyclooxygenase-inhibiting (COX-inhibiting) nonsteroidal antiinflammatory drugs (NSAIDs) is often complicated by renal side effects including hypertension and edema. The present studies were undertaken to elucidate the roles of COX1 and COX2 in regulating blood pressure and renal f...

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Udgivet i:J Clin Invest
Principais autores: Qi, Zhonghua, Hao, Chuan-Ming, Langenbach, Robert I., Breyer, Richard M., Redha, Reyadh, Morrow, Jason D., Breyer, Matthew D.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2002
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Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC151026/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12093889/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI14752
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