A new class of furoxan derivatives as NO donors: mechanism of action and biological activity.

1. The mechanism of action and biological activity of a series of R-substituted and di-R-substituted phenylfuroxans is reported. 2. Maximal potency as vasodilators on rabbit aortic rings, precontracted with noradrenaline (1 microM), was shown by phenyl-cyano isomers and by the 3,4-dicyanofuroxan, ch...

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Bibliografiska uppgifter
Huvudupphovsmän: Ferioli, R, Folco, G C, Ferretti, C, Gasco, A M, Medana, C, Fruttero, R, Civelli, M, Gasco, A
Materialtyp: Artigo
Språk:Inglês
Publicerad: 1995
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1510189/
https://ncbi.nlm.nih.gov/pubmed/7773542
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