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Myeloerythroid-restricted progenitors are sufficient to confer radioprotection and provide the majority of day 8 CFU-S

Whole-body irradiation at the minimal lethal dose causes bone marrow failure and death within 12–18 days. To identify the principal components of the hematopoietic system that are radioprotective, we transplanted lethally irradiated mice with purified progenitors: common myeloid progenitors (CMPs),...

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Detalhes bibliográficos
Main Authors: Na Nakorn, Thanyaphong, Traver, David, Weissman, Irving L., Akashi, Koichi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC151014/
https://ncbi.nlm.nih.gov/pubmed/12070305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI15272
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