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Myeloerythroid-restricted progenitors are sufficient to confer radioprotection and provide the majority of day 8 CFU-S

Whole-body irradiation at the minimal lethal dose causes bone marrow failure and death within 12–18 days. To identify the principal components of the hematopoietic system that are radioprotective, we transplanted lethally irradiated mice with purified progenitors: common myeloid progenitors (CMPs),...

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Autors principals: Na Nakorn, Thanyaphong, Traver, David, Weissman, Irving L., Akashi, Koichi
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2002
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC151014/
https://ncbi.nlm.nih.gov/pubmed/12070305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI15272
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