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Matrix metalloproteinase-7 is expressed by pancreatic cancer precursors and regulates acinar-to-ductal metaplasia in exocrine pancreas

In gastrointestinal epithelium, metaplastic conversion between predominant cell types is associated with an increased risk of neoplasia. However, the mechanisms regulating metaplastic transitions in adult epithelia are largely undefined. Here we show that matrix metalloproteinase-7 (MMP-7) is expres...

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Podrobná bibliografie
Vydáno v:J Clin Invest
Hlavní autoři: Crawford, Howard C., Scoggins, Charles R., Washington, M. Kay, Matrisian, Lynn M., Leach, Steven D.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2002
Témata:
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC150998/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12045257/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI15051
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