Pharmacological inhibition and reversal of pancreatic acinar ductal metaplasia

Abstract Pancreatic acinar cells display a remarkable degree of plasticity and can dedifferentiate into ductal-like progenitor cells by a process known as acinar ductal metaplasia (ADM). ADM is believed to be one of the earliest precursor lesions toward the development of pancreatic ductal adenocarc...

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Principais autores:	Lais da Silva, Jinmai Jiang, Corey Perkins, Kalina Rosenova Atanasova, Julie K. Bray, Gamze Bulut, Ana Azevedo-Pouly, Martha Campbell-Thompson, Xiaozhi Yang, Hesamedin Hakimjavadi, Srikar Chamala, Ranjala Ratnayake, Raad Z. Gharaibeh, Chenglong Li, Hendrik Luesch, Thomas D. Schmittgen
Format:	Artigo
Jezik:	Inglês
Izdano:	Nature Publishing Group 2022-09-01
Serija:	Cell Death Discovery
Online dostop:	https://doi.org/10.1038/s41420-022-01165-4
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