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Inhibition of rotavirus replication by a non-neutralizing, rotavirus VP6–specific IgA mAb

Rotaviruses are the leading cause of severe diarrheal disease in young children. Intestinal mucosal IgA responses play a critical role in protective immunity against rotavirus reinfection. Rotaviruses consist of three concentric capsid layers surrounding a genome of 11 segments of double-stranded RN...

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Udgivet i:J Clin Invest
Principais autores: Feng, Ningguo, Lawton, Jeffrey A., Gilbert, Joana, Kuklin, Nelly, Vo, Phuoc, Prasad, B.V. Venkataram, Greenberg, Harry B.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2002
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Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC150959/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11994409/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI14397
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