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Activation of NF-κB following detachment delays apoptosis in intestinal epithelial cells

We reported earlier that IL-1β, an NF-κB-regulated cytokine, was made by intestinal epithelial cells during detachment-induced apoptosis (anoikis) and that IL-1 was antiapoptotic for detached cells. Since surviving anoikis is a prerequisite for cancer progression and metastases, we are further explo...

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Detalles Bibliográficos
Main Authors: Yan, Sen Rong, Joseph, Robbie Randle, Rosen, Kirill, Reginato, Mauricio J, Jackson, Amanda, Allaire, Norman, Brugge, Joan S, Jobin, Christian, Stadnyk, Andrew W
Formato: Artigo
Idioma:Inglês
Publicado: 2005
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1509103/
https://ncbi.nlm.nih.gov/pubmed/16007176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.onc.1208810
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