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The flavonoid luteolin prevents lipopolysaccharide-induced NF-κB signalling and gene expression by blocking IκB kinase activity in intestinal epithelial cells and bone-marrow derived dendritic cells
The nuclear factor (NF)-κB transcriptional system is a major effector pathway involved in inflammation and innate immune responses. The flavonoid luteolin is found in various herbal extracts and has shown anti-inflammatory properties. However, the mechanism of action and impact of luteolin on innate...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Blackwell Science Inc
2005
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1782165/ https://ncbi.nlm.nih.gov/pubmed/15946255 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2005.02156.x |
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