Tomato Lycopene Extract Prevents Lipopolysaccharide-Induced NF-κB Signaling but Worsens Dextran Sulfate Sodium-Induced Colitis in NF-κB(EGFP) Mice

BACKGROUND: The impact of tomato lycopene extract (TLE) on intestinal inflammation is currently unknown. We investigated the effect of TLE on lipopolysaccharide (LPS)-induced innate signaling and experimental colitis. METHODOLOGY/PRINCIPAL FINDINGS: Mice were fed a diet containing 0.5 and 2% TLE or...

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Detalhes bibliográficos
Main Authors: Joo, Young-Eun, Karrasch, Thomas, Mühlbauer, Marcus, Allard, Brigitte, Narula, Acharan, Herfarth, Hans H., Jobin, Christian
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2642995/
https://ncbi.nlm.nih.gov/pubmed/19234608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0004562
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