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Cardiomyocyte overexpression of iNOS in mice results in peroxynitrite generation, heart block, and sudden death

Increased inducible nitric oxide synthase (iNOS) expression is a component of the immune response and has been demonstrated in cardiomyocytes in septic shock, myocarditis, transplant rejection, ischemia, and dilated cardiomyopathy. To explore whether the consequences of such expression are adaptive...

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Detalhes bibliográficos
Main Authors: Mungrue, Imran N., Gros, Robert, You, Xiaomang, Pirani, Asif, Azad, Azar, Csont, Tamas, Schulz, Richard, Butany, Jagdish, Stewart, Duncan J., Husain, Mansoor
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2002
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC150906/
https://ncbi.nlm.nih.gov/pubmed/11901182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI13265
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