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Cystin, a novel cilia-associated protein, is disrupted in the cpk mouse model of polycystic kidney disease

The congenital polycystic kidney (cpk) mutation is the most extensively characterized mouse model of polycystic kidney disease (PKD). The renal cystic disease is fully expressed in homozygotes and is strikingly similar to human autosomal recessive PKD (ARPKD), whereas genetic background modulates th...

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Hlavní autoři: Hou, Xiaoying, Mrug, Michal, Yoder, Bradley K., Lefkowitz, Elliot J., Kremmidiotis, Gabriel, D’Eustachio, Peter, Beier, David R., Guay-Woodford, Lisa M.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2002
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC150876/
https://ncbi.nlm.nih.gov/pubmed/11854326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI14099
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