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Proximal Tubule Proliferation Is Insufficient to Induce Rapid Cyst Formation after Cilia Disruption

Disrupting the function of cilia in mouse kidneys results in rapid or slow progression of cystic disease depending on whether the animals are juveniles or adults, respectively. Renal injury can also markedly accelerate the renal cyst formation that occurs after disruption of cilia in adult mice. Rat...

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Detalhes bibliográficos
Main Authors: Sharma, Neeraj, Malarkey, Erik B., Berbari, Nicolas F., O’Connor, Amber K., Vanden Heuvel, Gregory B., Mrug, Michal, Yoder, Bradley K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3582198/
https://ncbi.nlm.nih.gov/pubmed/23411784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2012020154
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