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Normal Th1 development following long-term therapeutic blockade of CD154-CD40 in experimental autoimmune encephalomyelitis

Experimental autoimmune encephalomyelitis (EAE) is a Th1-mediated demyelinating disease of the CNS with similarities to multiple sclerosis. We and others have shown that a short-term course of anti-CD154 mAb treatment to block CD154-CD40 interactions can be used to prevent or even treat ongoing PLP1...

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Bibliografiska uppgifter
Huvudupphovsmän: Howard, Laurence M., Ostrovidov, Serge, Smith, Cassandra E., Dal Canto, Mauro C., Miller, Stephen D.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Clinical Investigation 2002
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC150843/
https://ncbi.nlm.nih.gov/pubmed/11805135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI14374
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