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Targeting the CD40-CD154 Signaling Pathway for Treatment of Autoimmune Arthritis
Full activation of T lymphocytes requires signals from both T cell receptors and costimulatory molecules. In addition to CD28, several T cell molecules could deliver costimulatory signals, including CD154, which primarily interacts with CD40 on B-cells. CD40 is a critical molecule regulating several...
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| Published in: | Cells |
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| Main Authors: | , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
MDPI
2019
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6721639/ https://ncbi.nlm.nih.gov/pubmed/31426619 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells8080927 |
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