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Targeting the CD40-CD154 Signaling Pathway for Treatment of Autoimmune Arthritis

Full activation of T lymphocytes requires signals from both T cell receptors and costimulatory molecules. In addition to CD28, several T cell molecules could deliver costimulatory signals, including CD154, which primarily interacts with CD40 on B-cells. CD40 is a critical molecule regulating several...

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Detalhes bibliográficos
Publicado no:Cells
Main Authors: Lai, Jenn-Haung, Luo, Shue-Fen, Ho, Ling-Jun
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6721639/
https://ncbi.nlm.nih.gov/pubmed/31426619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells8080927
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