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Mechanisms of immunotherapeutic intervention by anti-CD40L (CD154) antibody in an animal model of multiple sclerosis

Relapsing experimental autoimmune encephalomyelitis (R-EAE) in the SJL mouse is a Th1-mediated autoimmune demyelinating disease model for human multiple sclerosis and is characterized by infiltration of the central nervous system (CNS) by Th1 cells and macrophages. Disease relapses are mediated by T...

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Autori principali: Howard, Laurence M., Miga, Amy J., Vanderlugt, Carol L., Canto, Mauro C. Dal, Laman, Jon D., Noelle, Randolph J., Miller, Stephen D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 1999
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC407886/
https://ncbi.nlm.nih.gov/pubmed/9916140
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