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Leptin modulates the effects of acyl CoA:diacylglycerol acyltransferase deficiency on murine fur and sebaceous glands

Acyl CoA:diacylglycerol acyltransferase (DGAT) is a ubiquitously expressed enzyme that catalyzes the final reaction in the major pathways of triglyceride synthesis. Mice lacking DGAT1 (Dgat(–/–)) demonstrate significant changes in lipid metabolism in several tissues, including the skin. Here we repo...

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Autors principals: Chen, Hubert C., Smith, Steven J., Tow, Bryan, Elias, Peter M., Farese, Robert V.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2002
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC150839/
https://ncbi.nlm.nih.gov/pubmed/11805129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI13880
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