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The cardiac phenotype induced by PPARα overexpression mimics that caused by diabetes mellitus

Recent evidence has defined an important role for PPARα in the transcriptional control of cardiac energy metabolism. To investigate the role of PPARα in the genesis of the metabolic and functional derangements of diabetic cardiomyopathy, mice with cardiac-restricted overexpression of PPARα (MHC-PPAR...

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書誌詳細
主要な著者: Finck, Brian N., Lehman, John J., Leone, Teresa C., Welch, Michael J., Bennett, Michael J., Kovacs, Attila, Han, Xianlin, Gross, Richard W., Kozak, Ray, Lopaschuk, Gary D., Kelly, Daniel P.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Clinical Investigation 2002
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC150824/
https://ncbi.nlm.nih.gov/pubmed/11781357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI14080
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