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The cardiac phenotype induced by PPARα overexpression mimics that caused by diabetes mellitus
Recent evidence has defined an important role for PPARα in the transcriptional control of cardiac energy metabolism. To investigate the role of PPARα in the genesis of the metabolic and functional derangements of diabetic cardiomyopathy, mice with cardiac-restricted overexpression of PPARα (MHC-PPAR...
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| Autors principals: | , , , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Clinical Investigation
2002
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC150824/ https://ncbi.nlm.nih.gov/pubmed/11781357 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI14080 |
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