Pneumococcal pneumolysin and H(2)O(2) mediate brain cell apoptosis during meningitis
Pneumococcus is the most common and aggressive cause of bacterial meningitis and induces a novel apoptosis-inducing factor–dependent (AIF–dependent) form of brain cell apoptosis. Loss of production of two pneumococcal toxins, pneumolysin and H(2)O(2), eliminated mitochondrial damage and apoptosis. P...
Zapisane w:
| Wydane w: | J Clin Invest |
|---|---|
| Główni autorzy: | , , , , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
American Society for Clinical Investigation
2002
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC150815/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11781347/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI12035 |
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