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Delta-1 enhances marrow and thymus repopulating ability of human CD34(+)CD38(–) cord blood cells

We investigated the effect of Notch signaling, a known regulator of cell fate in numerous developmental systems, on human hematopoietic precursors. We show that activation of endogenous Notch signaling in human CD34(+)CD38(–) cord blood precursors with immobilized Delta-1 in serum-free cultures cont...

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Bibliographic Details
Main Authors: Ohishi, Kohshi, Varnum-Finney, Barbara, Bernstein, Irwin D.
Format: Artigo
Language:Inglês
Published: American Society for Clinical Investigation 2002
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC150801/
https://ncbi.nlm.nih.gov/pubmed/12393852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI16167
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