An Alternate Splicing Variant of the Human Telomerase Catalytic Subunit Inhibits Telomerase Activity

Telomerase, a cellular reverse transcriptase, adds telomeric repeats to chromosome ends. In normal human somatic cells, telomerase is repressed and telomeres progressively shorten, leading to proliferative senescence. Introduction of the telomerase (hTERT) cDNA is sufficient to produce telomerase ac...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Yi, Xiaoming, White, Dennis M, Aisner, Dara L, Baur, Joseph A, Wright, Woodring E, Shay, Jerry W
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Nature America, Inc. 2000
विषय:
Research Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC1507981/
https://ncbi.nlm.nih.gov/pubmed/11191110
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