p53 Binding Protein 53BP1 Is Required for DNA Damage Responses and Tumor Suppression in Mice
53BP1 is a p53 binding protein of unknown function that binds to the central DNA-binding domain of p53. It relocates to the sites of DNA strand breaks in response to DNA damage and is a putative substrate of the ataxia telangiectasia-mutated (ATM) kinase. To study the biological role of 53BP1, we di...
Αποθηκεύτηκε σε:
| Εκδόθηκε σε: | Mol Cell Biol |
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| Κύριοι συγγραφείς: | , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Taylor & Francis
2003
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC150747/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12640136/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.23.7.2556-2563.2003 |
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