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p53 Binding Protein 53BP1 Is Required for DNA Damage Responses and Tumor Suppression in Mice
53BP1 is a p53 binding protein of unknown function that binds to the central DNA-binding domain of p53. It relocates to the sites of DNA strand breaks in response to DNA damage and is a putative substrate of the ataxia telangiectasia-mutated (ATM) kinase. To study the biological role of 53BP1, we di...
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| 主要な著者: | , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Microbiology
2003
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC150747/ https://ncbi.nlm.nih.gov/pubmed/12640136 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.7.2556-2563.2003 |
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