Modulation of Rab5 and Rab7 Recruitment to Phagosomes by Phosphatidylinositol 3-Kinase

Phagosomal biogenesis is central for microbial killing and antigen presentation by leukocytes. However, the molecular mechanisms governing phagosome maturation are poorly understood. We analyzed the role and site of action of phosphatidylinositol 3-kinases (PI3K) and of Rab GTPases in maturation usi...

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Detalhes bibliográficos
Main Authors: Vieira, Otilia V., Bucci, Cecilia, Harrison, Rene E., Trimble, William S., Lanzetti, Letizia, Gruenberg, Jean, Schreiber, Alan D., Stahl, Philip D., Grinstein, Sergio
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Cell and Organelle Structure and Assembly
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC150733/
https://ncbi.nlm.nih.gov/pubmed/12640132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.7.2501-2514.2003
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