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Modulation of Rab5 and Rab7 Recruitment to Phagosomes by Phosphatidylinositol 3-Kinase

Phagosomal biogenesis is central for microbial killing and antigen presentation by leukocytes. However, the molecular mechanisms governing phagosome maturation are poorly understood. We analyzed the role and site of action of phosphatidylinositol 3-kinases (PI3K) and of Rab GTPases in maturation usi...

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Autori principali: Vieira, Otilia V., Bucci, Cecilia, Harrison, Rene E., Trimble, William S., Lanzetti, Letizia, Gruenberg, Jean, Schreiber, Alan D., Stahl, Philip D., Grinstein, Sergio
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2003
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC150733/
https://ncbi.nlm.nih.gov/pubmed/12640132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.7.2501-2514.2003
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