Modulation of Rab5 and Rab7 Recruitment to Phagosomes by Phosphatidylinositol 3-Kinase

Phagosomal biogenesis is central for microbial killing and antigen presentation by leukocytes. However, the molecular mechanisms governing phagosome maturation are poorly understood. We analyzed the role and site of action of phosphatidylinositol 3-kinases (PI3K) and of Rab GTPases in maturation usi...

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Veröffentlicht in:	Mol Cell Biol
Hauptverfasser:	Vieira, Otilia V., Bucci, Cecilia, Harrison, Rene E., Trimble, William S., Lanzetti, Letizia, Gruenberg, Jean, Schreiber, Alan D., Stahl, Philip D., Grinstein, Sergio
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Taylor & Francis 2003
Schlagworte:	Cell and Organelle Structure and Assembly
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC150733/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12640132/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.23.7.2501-2514.2003
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