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Mycobacterium's Arrest of Phagosome Maturation in Macrophages Requires Rab5 Activity and Accessibility to Iron

Many mycobacteria are intramacrophage pathogens that reside within nonacidified phagosomes that fuse with early endosomes but do not mature to phagolysosomes. The mechanism by which mycobacteria block this maturation process remains elusive. To gain insight into whether fusion with early endosomes i...

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Bibliografiske detaljer
Main Authors: Kelley, Victoria A., Schorey, Jeffrey S.
Format: Artigo
Sprog:Inglês
Udgivet: The American Society for Cell Biology 2003
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC181573/
https://ncbi.nlm.nih.gov/pubmed/12925769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E02-12-0780
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