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Structural Requirements of SLP-76 in Signaling via the High-Affinity Immunoglobulin E Receptor (FcɛRI) in Mast Cells
The adapter SLP-76 plays an essential role in FcɛRI signaling, since SLP-76(−/−) bone marrow-derived mast cells (BMMC) fail to degranulate and release interleukin-6 (IL-6) following FcɛRI ligation. To define the role of SLP-76 domains and motifs in FcɛRI signaling, SLP-76(−/−) BMMC were retrovirally...
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| Autori principali: | , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Microbiology
2003
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC150723/ https://ncbi.nlm.nih.gov/pubmed/12640123 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.7.2395-2406.2003 |
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