Structural Requirements of SLP-76 in Signaling via the High-Affinity Immunoglobulin E Receptor (FcɛRI) in Mast Cells

The adapter SLP-76 plays an essential role in FcɛRI signaling, since SLP-76(−/−) bone marrow-derived mast cells (BMMC) fail to degranulate and release interleukin-6 (IL-6) following FcɛRI ligation. To define the role of SLP-76 domains and motifs in FcɛRI signaling, SLP-76(−/−) BMMC were retrovirally...

ver descrição completa

Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Kettner, Alexander, Pivniouk, Vadim, Kumar, Lalit, Falet, Hervé, Lee, Jeng-Shin, Mulligan, Richard, Geha, Raif S.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 2003
Assuntos:	Cell Growth and Development
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC150723/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12640123/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.23.7.2395-2406.2003
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!