Noninvasive gene transfer to the lung for systemic delivery of therapeutic proteins
This study evaluates the use of vectors based on adeno-associated viruses (AAVs) to noninvasively deliver genes to airway epithelial cells as a means for achieving systemic administration of therapeutic proteins. We intranasally delivered AAV vectors to mice in which the same AAV2 genome encoding a...
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| Udgivet i: | J Clin Invest |
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| Principais autores: | , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Clinical Investigation
2002
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC150421/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12189244/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI15780 |
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