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Cyclooxygenase-1–selective inhibition prolongs gestation in mice without adverse effects on the ductus arteriosus

Preterm delivery is the leading cause of neonatal mortality and contributes significantly to infant morbidity. Classical cyclooxygenase (COX) inhibitors, such as indomethacin, which inhibit both COX-1 and COX-2, are effective for delaying premature labor, but their use is limited by serious complica...

詳細記述

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書誌詳細
主要な著者: Loftin, Charles D., Trivedi, Darshini B., Langenbach, Robert
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Clinical Investigation 2002
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC150416/
https://ncbi.nlm.nih.gov/pubmed/12189249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI14924
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