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Pseudoachondroplasia is caused through both intra- and extracellular pathogenic pathways
Pseudoachondroplasia is a dominantly inherited chondrodysplasia associated with mutations in cartilage oligomeric matrix protein (COMP). Investigations into the pathogenesis of pseudoachondroplasia are hampered by its rarity. We developed a cell culture model by expressing mutant COMP in bovine prim...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2002
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC150414/ https://ncbi.nlm.nih.gov/pubmed/12189245 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI14386 |
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