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A Point Mutation in the Transmembrane Domain of the Hemagglutinin of Influenza Virus Stabilizes a Hemifusion Intermediate That Can Transit to Fusion
A hemagglutinin (HA) of influenza virus having a single semiconserved Gly residue within the transmembrane domain mutated to Leu (G520L) was expressed on cells; these cells were bound to red blood cells. By decreasing pH at 23°C rather than 37°C, an intermediate with properties expected of hemifusio...
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Main Authors: | , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
The American Society for Cell Biology
2000
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Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC15035/ https://ncbi.nlm.nih.gov/pubmed/11071905 |
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