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A Specific Point Mutant at Position 1 of the Influenza Hemagglutinin Fusion Peptide Displays a Hemifusion Phenotype

We showed previously that substitution of the first residue of the influenza hemagglutinin (HA) fusion peptide Gly1 with Glu abolishes fusion activity. In the present study we asked whether this striking phenotype was due to the charge or side-chain volume of the substituted Glu. To do this we gener...

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Bibliographic Details
Main Authors: Qiao, Hui, Armstrong, R. Todd, Melikyan, Grigory B., Cohen, Fredric S., White, Judith M.
Format: Artigo
Language:Inglês
Published: The American Society for Cell Biology 1999
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC25511/
https://ncbi.nlm.nih.gov/pubmed/10436026
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