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A role for N-glycanase in the cytosolic turnover of glycoproteins

Successful maturation determines the intracellular fate of secretory and membrane proteins in the endoplasmic reticulum (ER). Failure of proteins to fold or assemble properly can lead to their retention in the ER and redirects them to the cytosol for degradation by the proteasome. Proteasome inhibit...

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Bibliografiske detaljer
Udgivet i:EMBO J
Principais autores: Hirsch, Christian, Blom, Daniël, Ploegh, Hidde L.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2003
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC150340/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12606569/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/cdg107
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