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A role for N-glycanase in the cytosolic turnover of glycoproteins
Successful maturation determines the intracellular fate of secretory and membrane proteins in the endoplasmic reticulum (ER). Failure of proteins to fold or assemble properly can lead to their retention in the ER and redirects them to the cytosol for degradation by the proteasome. Proteasome inhibit...
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| Main Authors: | , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Oxford University Press
2003
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC150340/ https://ncbi.nlm.nih.gov/pubmed/12606569 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg107 |
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