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A role for N-glycanase in the cytosolic turnover of glycoproteins

Successful maturation determines the intracellular fate of secretory and membrane proteins in the endoplasmic reticulum (ER). Failure of proteins to fold or assemble properly can lead to their retention in the ER and redirects them to the cytosol for degradation by the proteasome. Proteasome inhibit...

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Detalles Bibliográficos
Publicado en:EMBO J
Principais autores: Hirsch, Christian, Blom, Daniël, Ploegh, Hidde L.
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2003
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC150340/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12606569/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/cdg107
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